Invasive Cornual Mole in a Pre-Menopausal Woman: About a Case and the Review of Literature

Cornual pregnancy is a rare form of ectopic pregnancy and only 2% to 4% of ectopic pregnancies develop in the cornual region of the uterus. Cornual pregnancy is one of the most dangerous types of ectopic pregnancy with a mortality rate of 2.0%-2.5%. Hydatidiform mole is a common form of gestational trophoblastic disease. The incidence of complete hydatidiform moles is approximately 1 to 3 per 1,000 pregnancies. An invasive hydatidiform mole can occur following a molar pregnancy and the incidence is 1 in 15,000 pregnancies.

We report one of the rarest pathologies: A patient suffering from an invasive cornual mole which remains extremely rare in a woman in pre-menopause. Although in the world literature the occurrence of gestational trophoblastic disease is generally in women of childbearing age, the diagnosis of invasive mole should always be considered. Hysterectomy remains a radical option available in a woman in peri-menopause, which was the therapeutic decision in our patient after a negative extension assessment with simple operative consequences.