Extramedullary Leukaemic Infiltration of the External Auditory Meatus: A Case Report and Literature Review

Extramedullary Leukaemic Infiltration of the External Auditory Meatus: A Case Report and Literature Review

Introduction: Extramedullary spread of Acute Myeloid Leukaemia most commonly affects the liver, spleen, lymph nodes, central nervous system and skin. Leukaemic infiltration of the temporal bone is rare and may mimic otitis, further delaying appropriate treatment. Methods: Case report and literature review. Results: A sixty-year-old patient with known ‘Acute Myeloid Leukaemia with myelodysplasia-related changes’ (>33% blasts with normal female karyotype at bone marrow aspirate) that was not dependent on supportive transfusions of blood products, presented with a year-long history of left otorrhoea refractory to antibiotic therapy.