Evaluation of Cytotoxic Potential of Ponceau 4r in Vicia faba

Evaluation of Cytotoxic Potential of Ponceau 4r in Vicia faba

Permitted synthetic food colours and additives have become a part of food stuffs to enhance taste and flavor. Ponceau-4R has been tested for its cytotoxicity in Vicia faba and the chromosomal aberrations observed at metaphase were chromatid separation, scattered metaphase, breakage and extrusion of chromosomes which is an indication of the mutagenic risk potential of this dye, especially at higher concentration. Thus it can lead to certain cytogenetic effects on human being also.