Development and Characterization of Enteric Coated Pectin Pellets Containing Mesalamine and Saccharomyces boulardii for targeted delivery to Colon site.

The confirmation of which was done by the gain in weight, clinical improvement in macroscopic and microscopic factors of induced colitis. These findings ensure that coated pellet formulation has promising potential for targeted drug delivery of mesalamine and S.bulardii to the colon as well as to improve the viability of probiotics and enhancement in the effectiveness of mesalamine in management of ulcerative colitis.