Design, Development and Evaluation of Ketotifen Fumarate Solid Lipid Nanoparticles

The aim of the present study is to develop Ketotifen Fumarate solid lipid nanoparticles and to evaluate them. Formulations were formulated by using three lipids at various proportions. Solid lipid nanoparticles were prepared by hot homogenization followed by ultra-sonication Suitable lipids (Triastearin, GMS andtechnique. The nanoparticles were evaluated Compritol), stabilizer (Soy lecithin) and surfactant (Poloxamer) were selected. FT-IR studies were carried to check drug-excipient compatibility. In the present study nine studies, release kinetics.