Comparison of Neuropeptide Innervation in Allergic and Nonallergic Rhinitis

Comparison of Neuropeptide Innervation in Allergic and Nonallergic Rhinitis

Background: Rhinitis can be induced by different mechanisms and involves several etiological agents. It is important to differentiate between allergic rhinitis (AR) and nonallergic rhinitis (NAR), as management differs for each.

Objective: We aimed to study the several biomarkers of allergic rhinitis and nonallergic rhinitis to investigate their potential as outcome measures in clinical intervention trials.

Materials and Methods: All study groups were compared in terms of mucociliary clearance time, air flow level, and various neuropeptids in nasal fluid. All groups were evaluated for asthma by a respiratory medicine specialist performing pulmonary function testing.