Clinical, Radiological, and Laboratory Assessment of a Family Affected by Primary Atrophic Rhinitis

Clinical, Radiological, and Laboratory Assessment of a Family Affected by Primary Atrophic Rhinitis

Background: Atrophic rhinitis may be primary (ozena) or secondary (e.g. to radiation therapy or surgery). It manifests as widening of the nasal cavity due to atrophy of the nasal mucosa, which is covered with foul-smelling crusts. Its etiology is not clear. Objectives: To present a large family with atrophic rhinitis showing a possible dominant trait.

Material and Methods: We report the results of clinical, genetic, and immunologic examinations performed on five subjects, who were members of the same family.