Clinical Practice Variability in the Management of Patients with Alveolar Proteinosis

Alveolar proteinosis is a diffuse lung disease characterized by the accumulation of an amorphous and lipoproteinaceous of inorganic powders and HIV infection. Characteristic bronchoalveolar lavage is diagnosticated (presence of positive PAS material in the alveoli (pulmonary surfactant). This disease can be congenital, primary/idiopathic (due to alteration of the stimulating factor of macrocytic colonies) or several clinical conditions like hematological diseases, inhalation proteinaceous material, PAS positive). Total lung lavage (TLL) is onsidered the gold standard treatment of this pathology.