Clinical Manifestation, Diagnosis and Histology of Ovarian Luteoma: Case Report of Female Virilisation and Review of the Literature

Clinical Manifestation, Diagnosis and Histology of Ovarian Luteoma: Case Report of Female Virilisation and Review of the Literature

Stromal luteoma has recently been called and classified in the steroid cell tumor subgroup by the World Health Organisation (WHO). It is a rare benign ovarian tumor, originated in the ovarian stromal-sex cords, and it has endocrine repercussion. Sex cord-stromal tumours include a heterogeneous group of neoplasms that represent 7% of the ovarian tumours; most of them produce steroid hormones with estrogenic and/or androgenic effects, thus allowing its early diagnosis. Stromal luteoma usually presents with hiperestrogenic manifestations. We present an exceptional case of stromal luteoma that produced androgens.