Clinical Diagnosis and Management of Septal Chondrosarcoma

Chondrosarcoma of the nasal septum is an extremely rare malignancy. Chondrosarcoma are known to be slow-growing, invasive and usually high-grade malignancies. They most commonly occur in middle-aged men. Histology remains the mainstay of diagnosis. We report a case of a 36-year-old man who presented with nasal obstruction for 2 months. Endoscopic examination showed a nasal septal mass occupying the nasal cavity. Radiological findings showed a large soft tissue mass arising from the septum and Filling the nasal cavity with partial erosion of the posterior bony nasal septum. The patient underwent endoscopic nasal resection. The microscopic and immunophenotypic findings were consistent with moderately differentiated chondrosarcoma. Clinical, radiological and therapeutic challenges are discussed.