Calcifying Epithelial Odontogenic Tumor (Pindborg): Review of the Literature and update

The calcifying epithelial odontogenic tumor (CEOT) or Pindborg tumor is a rare benign odontogenic neoplasm of the jaws that accounts for 1% of all odontogenic tumors. The typical clinical presentation is a slow-growing intraosseous mass that causes expansion of the affected mandible. Most often, it is associated with an impacted tooth, is asymptomatic but locally aggressive and requires biopsy for diagnosis. Since the first description in 1955, only 200 cases approximately have been reported. The aim of this article is to make a systematic review of the literature and an update of Pindborg tumor, emphasizing the importance to realize a suitable histologic diagnosis and a treatment with safety margins to minimize the likelihood of recurrence.