Beneficial Effects of Sardine Proteins Combined with Citrus latifolia Extract on Lipid profile and Tissues Redox Status in Rats fed a High-Cholesterol Diet

Beneficial Effects of Sardine Proteins Combined with Citrus latifolia Extract on Lipid profile and Tissues Redox Status in Rats fed a High-Cholesterol Diet

Considerable evidences support the role of oxidative stress in the development of atherosclerosis and related cardiovascular diseases. Moreover, feeding experimental animals with high cholesterol diet (HCD) was reported to increase oxidative stress and to induce reactive oxygen species (ROS) generation in different biological tissues including liver, brain, kidney and erythrocytes. Also, lipid peroxidation and oxidative stress are one of the most important pathological mechanisms that explain metabolic changes and hepatic injury following HCD feeding