Basal Cell (Monomorphic) Adenoma of the Eyelid

Basal Cell Adenoma (BCA) is an uncommon benign salivary gland epithelial neoplasm composed of basaloid cells lacking chondromyxoid stroma. BCA occurring in the eyelid is an extremely rare finding. We describe a case of BCA arising in the upper eyelid of a 30-year-old woman. A well-demarcated subcutaneous nodule arising in the eyelid was composed of islands of uniform basaloid cells arranged in tubular and trabecular patterns and ductal and myoepithelial cells surrounded by hyaline basement membrane material. Immunohistochemically, luminal cells stained positive for CK7 and CD117, myoepithelial cells stained with p63 and both luminal and myoepithelial cells stained with SOX10 confirming the diagnosis of BCA. Further pathological characteristics of this disease are discussed.