Association of Antisperm Antibodies with Bacterial Infection: An Insight to Infertility

Association of Antisperm Antibodies with Bacterial Infection: An Insight to Infertility

Among other factors, immunological predictors associated with humoral immunity against sperm antigens can be a reason for human infertility. A hypothesis for the induction of antisperm antibodies (ASA) is the cross-reactivity of spermatozoa antigens and exogenous antigens. Common antigenicity has been established between spermatozoa and bacteria, viruses, fungi and allergens. Recent evidence suggests that many antigens shared among unrelated cell types are surface membrane or lipid conjugate complex carbohydrates.