Association of 8 Snps with Metabolic Changes in Type 2 Diabetes Mellitus in the Kazakh Population

Introduction: The steady growth of patients with type 2 diabetes mellitus (T2D) in the Republic of Kazakhstan over the past decade indicates the need to develop a program for the prevention of T2D. A change in the expression of candidate genes can lead to impaired insulin synthesis, a decrease in the number of insulin receptors, β-cell dysfunction, and obesity. The purpose of this study is to analyze the association of the SNPs with biochemical and anthropometric parameters of T2D in representatives of the Kazakh population.