Application of NeedlEx® to the Analysis of N-methyl O-aryl Carbamates in Urine and Serum Samples

The use of carbamates has been implicated in several suicides and in accidental poisoning. Rapid identification of these carbamates in clinical samples can direct the course of medical intervention and help save lives. In this study, we describe a new, operationally simple, and rapid method that employs a gas chromatograph (GC) or gas chromatograph-mass spectrometer (GC-MS) coupled to a NeedlEx® to analyze such toxic carbamates. NeedlEx®, a needle packed with media for the selective adsorption of volatile organic compunds, is idealy suited for use in such methods.