Antileishmanial Potential of Chondrococcus hornemanni against Experimental Visceral Leishmaniasis

 Antileishmanial Potential of Chondrococcus hornemanni against Experimental Visceral Leishmaniasis

Exploration of safe and effective antileishmanials from natural resources is an active area of research. Therefore we have selected C. hornemanni to evaluate its antileishmanial potential. The crude ethanol extract and its fractions were tested both in vitro and in vivo. The crude ethanol extract yielded almost (88.0 ± 6.9% inhibition of promastigotes and 75.8 ± 5.2% inhibition of intracellular amastigotes at 100 μg/ml concentration with IC50 values of 29.5 μg/ml and 40.6 μg/ml, respectively.