Analgesic Efficacy of Intravenous Paracetamol Plus Tramadol Combination for Pain after Laparoscopic Cholecystectomy: A Double-Blind, Randomized, Placebo-Controlled Trial

 Analgesic Efficacy of Intravenous Paracetamol Plus Tramadol Combination for Pain after Laparoscopic Cholecystectomy: A Double-Blind, Randomized, Placebo-Controlled Trial

Since first reported in 1987, laparoscopic cholecystectomy has become a popular technique worldwide because of its several advantages over conventional cholecystectomy. These advantages include less pain, more rapid convalescence, earlier discharge, and more expeditious return to normal activities. However, patients undergoing laparoscopic cholecystectomy still experience moderate to severe pain in the abdomen or shoulder region, especially on the first postoperative day. Appropriate postoperative pain management is therefore indicated.