Towards a West Nile Virus Vaccine

Towards a West Nile Virus Vaccine

West Nile virus (WNV) is a significant mosquito-borne human pathogen belonging to the Flaviviridae family with dengue, yellow fever, and Japanese encephalitis viruses. Recently, WNV has emerged as an important public health concern in the Western hemisphere, where it has established an endemic zoonotic cycle. Outcomes of WNV infection range from benign, non-symptomatic infection to flu-like febrile illness to severe central nervous system (CNS) manifestations.