Spanish 
Chinese 
Russian 
German 
French 
Japanese 
Portuguese 
Hindi Research Article, J Appl Bioinform Comput Biol Vol: 4 Issue: 2
A Computational Comparative study of α-Glucosidase Enzyme Divergence
| Mohammad Hossein Mehraban1,2, Younes Ghasemi2 and Sadeq Vallian1* | |
| 1Division of Genetics, Department of Biology, Faculty of Science, University of Isfahan, Isfahan, IR Iran | |
| 2Department of Pharmaceutical Biotechnology, Faculty of Pharmacy and Pharmaceutical Sciences Research Centre, Shiraz University of Medical Sciences, Shiraz, IR Iran | |
| Corresponding author : Dr. Sadeq Vallian Division of genetics, Department of Biology, Faculty of Science, University of Isfahan, Isfahan, Iran, Tel:983117932456 E-mail: svallian@sci.ui.ac.ir |
|
| Received: June 23, 2015 Accepted: August 07, 2015 Published: August 14 2015 | |
| Citation: Mehraban MH, Ghasemi Y, Vallian S (2015) A Computational Comparative study of a-Glucosidase enzyme Divergence. J Appl Bioinform Comput Biol 4:1. doi:10.4172/2329-9533.1000116 |
Abstract
A Computational Comparative study of α-Glucosidase enzyme Divergence
α-Glucosidase (α-Gls) enzymes have a crucial role in digestion of carbohydrates and biosynthesis of glycoproteins. Theses enzymes hydrolyze terminal glycosidic bonds and release α-glucose from the substrate chain. They are found in prokaryotic cells, plants and mammalian tissues such as liver, blood and especially intestine. The last step of carbohydrate digestion is catalyzed by α-glucosidases (namely maltase-glucoamylase or MGAM in mammals) which results in liberation of glucose.
