Research Article, J Regen Med Vol: 4 Issue: 2
Use of Autologous Adipose- Derived Stromal Vascular Fraction to Treat Osteoarthritis of the Knee: A Feasibility and Safety Study
| Jaime R Garza1*, Daniel Santa Maria2, Timothy Palomera2, Gregory A Dumanian3 and Severiano Dos-Anjos4 |
| 1School of Medicine, The University of Texas Health Science Center at San Antonio, Texas, USA |
| 2Sports Medicine Associates of San Antonio, Texas, USA |
| 3Neurologic Surgery and Orthopedic Surgery, Northwestern University- Feinberg School of Medicine, Chicago, Illinois, USA |
| 4Stem-Center, Palma, Mallorca, Spain |
| Corresponding author : Jaime R. Garza, MD, DDS 21 Spurs Lane, Suite 120, San Antonio, Texas 78240, USA Tel: 210-6160301; Fax: 210-6160302 E-mail: jrgmd@txps.net |
| Received: December 23, 2014 Accepted: March 12, 2015 Published: March 16, 2015 |
| Citation: Garza JR, Santa Maria D, Palomera T, Dumanian GA, Dos-Anjos S (2015) Use of Autologous Adipose-Derived Stromal Vascular Fraction to Treat Osteoarthritis of the Knee: A Feasibility and Safety Study. J Regen Med 4:1. doi:10.4172/2325-9620.1000119 |
Abstract
Autologous adipose-derived stromal vascular fraction (SVF) was used to treat ten osteoarthritic knees of grades II or III (K-L scale) under an IRB-approved protocol in a feasibility and safety study. The primary objective of this study was to determine if adipose-derived SVF can be safely used for intra-articular injection of the knee. The secondary objective of this study was to evaluate the feasibility of an intra-articular injection of adipose-derived SVF for pain relief in osteoarthritic knees.
