Case Report, J Otol Rhinol Vol: 4 Issue: 1
Sestamibi Localization of a Parathyroid Adenoma in the Presence of a Thymoma: a Case Report and Review of the Literature
| Andrew M. Hinson1,2, H. Gareth Tobler3, Chien Chen4, Tracy L.Yarbrough6, Donald L. Bodenner2,5, Brendan C. Stack, Jr.1,2* | |
| 1Department of Otolaryngology-Head and Neck Surgery, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA | |
| 2University of Arkansas for Medical Sciences Thyroid Center, Little Rock,Arkansas, USA | |
| 3Division of Cardiothoracic Surgery, University of Arkansas for Medical Sciences,Little Rock, Arkansas, USA | |
| 4Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA | |
| 5Department of Geriatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA | |
| 6Dept of Pharmacology & Physiology, George Washington University,Washington, DC, USA | |
| Corresponding author : Brendan C. Stack, Jr. MD, 4303 W. Markham St. #543, Little Rock, Arkansas 72205, USA Tel: 501-686-5140; Fax: 501-686-8029 E-mail: bstack@uams.edu |
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| Received: August 18, 2014 Accepted: October 04, 2014 Published: January 27, 2015 | |
| Citation: Hinson AM, Tobler HG, Chen C, Yarbrough TL, Bodenner DL, et al. (2015) Sestamibi Localization of a Parathyroid Adenoma in the Presence of a Thymoma: A Case Report and Review of the Literature. J Otol Rhinol 4:1. doi:10.4172/2324-8785.1000205 |
Abstract
Sestamibi Localization of a Parathyroid Adenoma in the Presence of a Thymoma: a Case Report and Review of the Literature
Preoperative localization in the surgical management of primary hyperparathyroidism is complicated by widely variable parathyroid gland anatomy, coexisting thyroid pathology, incidence of supernumerary and ectopic parathyroid glands, and limitations of targeted imaging studies. Technetium 99mTcsestamibi scans have decreased accuracy, sensitivity and specificity in the presence of multi-gland parathyroid disease. A number of reports suggest that thymomas, which also show increased sestamibi uptake, are potential sources of false positives on 99mTc-sestamibi scans. Herein, we describe a thymoma in association with a parathyroid adenoma complicating localization of hyperfunctional parathyroid tissue. We review the literature of concurrent pathology between parathyroid adenomas and thymomas paying particular attention to how these cases present on preoperative 99mTcsestamibi scans.
