The journal Cell Biology: Research & Therapy (CBRT) promotes rigorous research that makes a significant contribution in advancing knowledge in the fields of cell and molecular biology.
Cell Biology: Research & Therapy is a subscription based journal that provides a range of options to purchase our articles and also permits unlimited Internet Access to complete Journal content. It accepts research, review papers, online letters to the editors & brief comments on previously published articles or other relevant findings in SciTechnol. Articles submitted by authors are evaluated by a group of peer review experts in the field and ensures that the published articles are of high quality, reflect solid scholarship in their fields, and that the information they contain is accurate and reliable.
Future of Medical Practice and the Key Roll of Cell Biology; Bench to Beside
Cells are the fundamental unit of life and cell biology lies at heart of biomedical research. Cell Biology therefore defines the very center of all efforts to understand all aspects of human disease. All diseases are disturbances at the cellular level. To treat disease, we must understand the alterations that occur at the level of individual cells. The complementary nature of many of the researches generates a highly interactive and collaborative environment that promotes the development of novel approaches to address fundamental biological questions.
An important part of the classical drug discovery paradigm is the cell based assay. Medicinal chemists, after identification of the molecular target such as enzyme or receptor are quite efficient with the design and synthesis of a potential inhibitor or receptor antagonist. If crystal structure of the target proteins is available, computer modeling accelerated the overall process substantially. Also the combinatorial libraries could supply a large number of interesting new chemical structures. In a relative short time, medicinal chemistry could create a large number of the potent inhibitors or receptor antagonists.
Nutriepigenetics and Related Topics: From Cell Mechanisms to Possible Therapeutic Relevance
Nutritional genomics (nutrigenomics) is a broad field that relates the genome to nutrition, and includes the effects of dietary components on the expression of genes and on the repair of genetic damage. Bioactive forms of vitamin A (retinoids) and D (calciferols), for example, can modulate gene expression programs and thereby affect reproduction, development, and many other physiological functions.
Roles of Mitochondrial DNA Changes on Cancer Initiation and Progression
Mitochondria are essential organelles that generate ATP through oxidative phosphorylation. This process is accomplished by a series of protein complexes and mitochondrial respiratory chains (MRC) encoded by nuclear DNA and mitochondrial DNA (mtDNA).